Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15370695 | 0.92 | HTT (0.50) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL854814 | 0.89 | TSHR (0.48) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL27560611 | 0.88 | TSHR (0.40) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL838422 | 0.86 | ADRB2 (0.38) | TSHRCYP3A4SMN1; SMN2ALDH1A1ADRB2 | |
| SCHEMBL10893263 | 0.83 | TSHR (0.43) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL8083875 | 0.81 | ADRB2 (0.38) | TSHRCYP3A4SMN1; SMN2ALDH1A1ADRB2 | |
| SCHEMBL7110603 | 0.80 | TSHR (0.44) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL7111658 | 0.80 | TSHR (0.44) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL8607727 | 0.79 | TSHR (0.48) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL6295813 | 0.79 | DNM1 (0.35) | TSHRMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212063-B1 | URETHANE RESINS CONTAINING HYDROLYZABLE MOIETIES FROM ORGANOSILANE COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1990-09-05 | — | — | EP | disclosed |
| US-4913972-A | Transparent coating system for providing long term exterior durability to wood | PPG INDUSTRIES, INC. (US) | 1990-04-03 | — | — | US | disclosed |
| US-4808663-A | FOR LOW TEMPERATURE, MOISTURE, CATALYTIC CURING COATINGS | PPG INDUSTRIES, INC. (US) | 1989-02-28 | — | — | US | disclosed |
| US-4788107-A | ADHESIVES, SEALANTS, INKS | PPG INDUSTRIES, INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0278305-A1 | Transparent coating system for providing long term exterior durability to wood | PPG INDUSTRIES, INC. (US) | 1988-08-17 | — | — | EP | disclosed |
| US-4714738-A | CURABLE AT LOW TEMPERATURE | PPG INDUSTRIES, INC. (US) | 1987-12-22 | — | — | US | disclosed |
| EP-0234308-A2 | Coating composition containing an ungelled reaction product as a curative | PPG INDUSTRIES, INC. (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0231514-A2 | Compositions based on resins having silicon atoms attached to hydrolyzable groups derived from vinyl silanes and mercaptofunctional compounds | PPG INDUSTRIES, INC. (US) | 1987-08-12 | — | — | EP | disclosed |
| US-4684697-A | Compositions based on silane hydrolyzates and vinyl polymers containing hydrolyzable silyl groups | PPG INDUSTRIES, INC. (US) | 1987-08-04 | — | — | US | disclosed |
| US-4678835-A | AMINE AND SILICON-CONTAINING | PPG INDUSTRIES, INC. (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0216320-A2 | Compositions containing resins having air-oxidizable groups and epoxy groups and epoxy-reactive silicon-containing compounds having hydrolyzable groups | PPG INDUSTRIES, INC. (US) | 1987-04-01 | — | — | EP | disclosed |
| US-4652610-A | FLEXIBLE COATINGS; AUTOMOBILE PAINTS | PPG INDUSTRIES, INC. (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0212063-A1 | Urethane resins containing hydrolyzable moieties from organosilane compounds | PPG INDUSTRIES, INC. (US) | 1987-03-04 | — | — | EP | disclosed |
| EP-0203391-A2 | Ungelled resins containing hydrolyzable moieties from organosilane compounds | PPG INDUSTRIES, INC. (US) | 1986-12-03 | — | — | EP | disclosed |
| US-4623697-A | Ungelled resins containing hydrolyzable moieties from organosilane compounds | PPG INDUSTRIES, INC. (US) | 1986-11-18 | — | — | US | disclosed |
| US-4622369-A | Urethane resins containing hydrolyzable moieties from organosilane compounds | PPG INDUSTRIES, INC. (US) | 1986-11-11 | — | — | US | disclosed |
| US-4614766-A | Compositions containing resins having air-oxidizable groups and epoxy groups and epoxy-reactive silicon-containing compounds having hydrolyzable groups | PPG INDUSTRIES, INC. (US) | 1986-09-30 | — | — | US | disclosed |