SCHEMBL837875

SCHEMBL837875

CCCCO[Si](C)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1189490 1.00 ADRB2 (0.38) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL6292792 0.92 CA1 (0.33) TSHRALDH1A1CA1CA2CA12
SCHEMBL93421 0.92 ADRB2 (0.43) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL1608650 0.88 ADRB2 (0.33) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL9222954 0.86 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL10893263 0.86 TSHR (0.43) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL836809 0.83
SCHEMBL661810 0.83 THRB (0.39) TSHRALDH1A1CA1CA2CA12
SCHEMBL8470089 0.83
SCHEMBL662288 0.81 THRB (0.44) TSHRALDH1A1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545809-B2 Moisture-curing conformal coating compositions WACKER CHEMIE AG (DE) 2026-02-10 US disclosed
EP-4172246-B1 MOISTURE-CURING CONFORMAL COATING COMPOSITIONS WACKER CHEMIE AG (DE) 2024-08-07 EP disclosed
US-20230279263-A1 MOISTURE-CURING CONFORMAL COATING COMPOSITIONS WACKER CHEMIE AG (DE) 2023-09-07 US disclosed
EP-4172246-A1 MOISTURE-CURING CONFORMAL COATING COMPOSITIONS Wacker Chemie AG (DE) 2023-05-03 EP disclosed
WO-2021259460-A1 MOISTURE-CURING CONFORMAL COATING COMPOSITIONS WACKER CHEMIE AG (DE) 2021-12-30 WO disclosed
EP-1904415-B1 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING (US) 2014-03-12 EP disclosed
EP-2625233-A1 BIODEGRADABLE HYDROPHOBIC CELLULOSIC SUBSTRATES AND METHODS FOR THEIR PRODUCTION USING REACTIVE SILANES Dow Corning Corporation (US) 2013-08-14 EP disclosed
US-20130190429-A1 Biodegradable Hydrophobic Cellulosic Substrates And Methods For Their Production Using Reactive Silanes DOW CORNING CORPORATION (US) 2013-07-25 US disclosed
CN-103154165-A Biodegradable hydrophobic cellulosic substrates and methods for their production using reactive silanes DOW CORNING 2013-06-12 CN disclosed
CN-101223117-B Hydrophobing minerals and filler materials DOW CORNING 2013-03-27 CN disclosed
US-4152343-A REACTING AN ORGANIC SILICATE OR SILANETRIOL DERIVATIVE WITH A DIALKYLTIN CAROXYLIC ACID SALT WACKER-CHEMIE GMBH (DE) 1979-05-01 US disclosed
US-4137249-A Silicon-tin compounds WACKER-CHEMIE GMBH (DE) 1979-01-30 US disclosed
US-4133938-A ACRYLOYLOXYALKYLALKOXYSILANE-ACRYLATE REACTION PRODUCT, MASONRY SWS SILICONES CORPORATION (US) 1979-01-09 US disclosed
US-4123472-A POLYMERIZING ACRYLIC ESTERS AND NITRILES IN THE PRESENCE OF ORGANOPOLYSILOXANES AND FREE RADICAL CATALYST, CROSSLINKING SWS SILICONES CORPORATION (US) 1978-10-31 US disclosed
US-4102860-A ROOM TEMPERATURE CURING WACKER-CHEMIE GMBH (DE) 1978-07-25 US disclosed
US-4076684-A GLASS FIBERS; CURABLE WACKER-CHEMIE GMBH (DT) 1978-02-28 US disclosed
US-4045602-A ADHESION OF ORGANOPOLYSILOXANE ELASTOMERS TO SUBSTRATES WACKER-CHEMIE GMBH (DT) 1977-08-30 US disclosed
US-4032499-A GRAFT POLYMERIZATION USING FREE RADICAL CATALYST, NONSOLVENT CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DT) 1977-06-28 US disclosed
US-4026853-A Curable bituminous organopolysiloxane compositions CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DT) 1977-05-31 US disclosed
US-3989790-A Method for preparing silicone rubber molds SWS SILICONES CORPORATION (US) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545809-B2 Moisture-curing conformal coating compositions COL1A1, COL2A1, MSR1 ADRB2 1938/4885ADRB1 2330/4885ADRB3 1694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.