Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898456 | 0.86 | ALDH1A1 (0.44) | SLC22A2SLC22A1SLC22A3NPC1MAPT | |
| SCHEMBL7948183 | 0.76 | TSHR (0.71) | TSHRSLC22A2SLC22A1SLC22A3KIF11 | |
| SCHEMBL166690 | 0.74 | TSHR (1.00) | TSHRSLC22A2SLC22A1SLC22A3KIF11 | |
| SCHEMBL5495871 | 0.74 | TSHR (1.00) | TSHRSLC22A2SLC22A1SLC22A3KIF11 | |
| SCHEMBL10897691 | 0.74 | CYP2A6 (0.44) | TSHRALDH1A1CYP2A6PLAU | |
| SCHEMBL10898807 | 0.74 | ACHE (0.56) | TSHRNPC1MAPTRAB9ALMNA | |
| Hydrogen Sulfide SCHEMBL27843123 | 0.72 | TSHR (0.94) | TSHRSLC22A2SLC22A1SLC22A3KIF11 | |
| SCHEMBL25494719 | 0.70 | SLC22A2 (0.47) | TSHRSLC22A2SLC22A1SLC22A3KIF11 | |
| SCHEMBL827333 | 0.70 | TSHR (0.50) | TSHRSLC22A2SLC22A1SLC22A3KIF11 | |
| SCHEMBL1434985 | 0.70 | P2RY6 (0.50) | TSHRSLC22A2SLC22A1SLC22A3KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585574-A | POSITIVE DIELECTRIC ANISOTROPY | BAYER AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | claimed |