Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | KIF11 | P52732 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868881 | 0.90 | KIF11 (0.56) | TSHRKIF11NPC1MAPTRAB9A | |
| SCHEMBL166690 | 0.84 | TSHR (1.00) | TSHRKIF11NPC1MAPTRAB9A | |
| SCHEMBL5495871 | 0.84 | TSHR (1.00) | TSHRKIF11NPC1MAPTRAB9A | |
| Hydrogen Sulfide SCHEMBL27843123 | 0.82 | TSHR (0.94) | TSHRKIF11NPC1MAPTRAB9A | |
| SCHEMBL219074 | 0.82 | ALDH1A1 (0.58) | TSHRALDH1A1LMNACYP2A6ACHE | |
| SCHEMBL24522303 | 0.77 | TSHR (0.83) | TSHRKIF11NPC1MAPTRAB9A | |
| SCHEMBL19192713 | 0.77 | TSHR (0.83) | TSHRKIF11NPC1MAPTRAB9A | |
| SCHEMBL24599236 | 0.77 | TSHR (0.83) | TSHRKIF11NPC1MAPTRAB9A | |
| SCHEMBL28126518 | 0.77 | TSHR (0.83) | TSHRKIF11NPC1MAPTRAB9A | |
| SCHEMBL10895992 | 0.76 | TSHR (0.56) | TSHRKIF11NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300433-B1 | Olefin copolymerization process with bridged hafnocenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-10-09 | — | — | US | disclosed |