Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701737 | 0.74 | MAOA (1.00) | MAOAMAOBKMT2AMEN1RAB9A | |
| SCHEMBL4495770 | 0.73 | MAOA (0.42) | MAOAMAOBKMT2AMEN1NPC1 | |
| SCHEMBL2519252 | 0.73 | MAOA (0.54) | MAOAMAOBKMT2AMEN1MAPT | |
| SCHEMBL15249113 | 0.71 | MEN1 (0.66) | CNR1CNR2KMT2AMEN1NPC1 | |
| SCHEMBL10349749 | 0.71 | PARP10 (0.71) | CNR1CNR2KMT2AMEN1NPC1 | |
| SCHEMBL1079030 | 0.70 | ALDH1A1 (0.46) | MAOAMAOBKMT2AMEN1MAPT | |
| SCHEMBL5609808 | 0.70 | NPC1 (0.64) | CNR1CNR2KMT2AMEN1NPC1 | |
| SCHEMBL9446245 | 0.70 | MEN1 (0.64) | CNR1CNR2KMT2AMEN1NPC1 | |
| SCHEMBL31012122 | 0.68 | CYP1A2 (0.56) | CNR1CNR2KMT2AMEN1NPC1 | |
| SCHEMBL4850585 | 0.68 | CYP1A2 (0.56) | CNR1CNR2KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590301-A | USING PHENOL OR DIKETONE CYCLOHEXYL COMPOUNDS | BARNES-HIND, INC. (US) | 1986-05-20 | — | — | US | claimed |