Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077009 | 0.77 | MAOA (0.46) | MAOAMAOBERBB2ALDH1A1KDM4E | |
| SCHEMBL29465674 | 0.76 | MAOA (0.45) | MAOAMAOBERBB2ALDH1A1KDM4E | |
| SCHEMBL442767 | 0.73 | HTR1B (0.54) | ALDH1A1KDM4EGAAL3MBTL1MAPT | |
| SCHEMBL29577853 | 0.73 | HTR1B (0.54) | ALDH1A1KDM4EGAAL3MBTL1MAPT | |
| SCHEMBL10896758 | 0.73 | MAOA (0.58) | MAOAMAOBALDH1A1MAPTNPSR1 | |
| SCHEMBL1079030 | 0.73 | ALDH1A1 (0.46) | MAOAMAOBALDH1A1KDM4EGAA | |
| Formaldehyde SCHEMBL28332208 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAL3MBTL1MAPT | |
| Methane SCHEMBL10959030 | 0.71 | HTR1B (0.52) | ALDH1A1KDM4EGAAL3MBTL1MAPT | |
| Lithium SCHEMBL6571336 | 0.71 | HTR1B (0.52) | ALDH1A1KDM4EGAAL3MBTL1MAPT | |
| SCHEMBL7457103 | 0.71 | HTR1B (0.52) | ALDH1A1KDM4EGAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488820-B2 | Naphthofluorescein-based metal sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-02-10 | — | — | US | disclosed |
| US-20050186555-A1 | Naphthofluorescein-based metal sensors, and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-08-25 | — | — | US | disclosed |
| WO-2005067580-A2 | NAPHTHOFLUORESCEIN-BASED METAL SENSORS, AND METHODS OF MAKING AND USING THE SAME | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050186555-A1 | Naphthofluorescein-based metal sensors, and methods of making and using the same | NCF1, NDUFV2, NQO1 | MAOA 1175/4885MAOB 1397/4885ERBB2 4577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.