Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 1.00 |
| ▸ | MAOB | P27338 | 4/20 | 1.00 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273631 | 0.83 | MAOA (0.70) | MAOAMAOBTOP1 | |
| SCHEMBL28858701 | 0.81 | MAOA (0.68) | MAOAMAOBTOP1HTTGSTP1 | |
| SCHEMBL6216372 | 0.78 | MAOB (0.63) | MAOAMAOBTOP1HTTGSTP1 | |
| SCHEMBL10896758 | 0.74 | MAOA (0.58) | MAOAMAOBHTTLMNACYP1A2 | |
| SCHEMBL8927435 | 0.74 | MAOA (0.58) | MAOAMAOBTOP1ERBB2HSD17B3 | |
| SCHEMBL20087538 | 0.73 | MAOA (0.57) | MAOAMAOBERBB2MAPTHSD17B3 | |
| SCHEMBL23181355 | 0.71 | MAOB (0.56) | MAOAMAOBTOP1HTTGSTP1 | |
| SCHEMBL8460927 | 0.71 | GAPDH (0.57) | MAOAMAOBTOP1GSTP1L3MBTL1 | |
| SCHEMBL5595832 | 0.71 | PTPRC (0.65) | MAOAMAOBL3MBTL1NSD2LMNA | |
| SCHEMBL6267410 | 0.71 | MAOA (0.55) | MAOAMAOBERBB2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968192-A | Skin care formulations | 美国陶氏有机硅公司 | 2025-05-09 | — | — | CN | disclosed |
| US-20040049056-A1 | Process for preparation of esculetin compounds, esculetin compounds and intermediates thereof, and use of both | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1357118-A1 | PROCESS FOR PREPARATION OF ESCULETIN COMPOUNDS, ESCULETIN COMPOUNDS AND INTERMEDIATES THEREOF, AND USE OF BOTH | Kureha Chemical Industry Co., Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049056-A1 | Process for preparation of esculetin compounds, esculetin compounds and intermediates thereof, and use of both | SUCLG1, SALL4, HSD17B14 | MAOA 1664/4885MAOB 725/4885TOP1 2658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.