Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | METAP1 | P53582 | 2/20 | 0.47 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681942 | 0.81 | PTGS1 (0.63) | KDM4EMETAP1NFKB1ALDH1A1HSD17B10 | |
| SCHEMBL10896115 | 0.81 | RAB9A (0.45) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL10898501 | 0.81 | HTR2C (0.54) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL10897771 | 0.81 | HSD17B1 (0.58) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| Nabumetone SCHEMBL2256 | 0.80 | CYP1A2 (1.00) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| Nabumetone SCHEMBL29570823 | 0.80 | CYP1A2 (1.00) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| Nabumetone SCHEMBL29373228 | 0.80 | CYP1A2 (1.00) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| Nabumetone SCHEMBL3853067 | 0.80 | CYP1A2 (1.00) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL10899522 | 0.79 | RAB9A (0.47) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL10897456 | 0.79 | RAB9A (0.44) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581377-A | ANTIINFLAMMATORY, ANTIPYRETIC, AND ANALGESIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1986-04-08 | — | — | US | disclosed |