SCHEMBL10898034

SCHEMBL10898034

C=CCN(CC=C)c1ccc(NCC(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.40
GAA P10253 1/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP1A2 P05177 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
NOX1 Q9Y5S8 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
ALDH1A1 P00352 1/20 0.35
CHKA P35790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2361630 0.79 CA1 (0.50) NR4A1GAAMAPTMEN1KMT2A
SCHEMBL11309181 0.78 RAB9A (0.60) GAAMAPTMEN1KMT2ANPC1
SCHEMBL9133019 0.78 MAPT (0.49) NR4A1GAAMAPTMEN1KMT2A
SCHEMBL11093327 0.77 PEPD (0.48) NR4A1GAAMAPTMEN1KMT2A
SCHEMBL5692310 0.76 ALDH1A1 (0.44) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL11082545 0.76 CA1 (0.41) NR4A1GAAMAPTMEN1KMT2A
SCHEMBL11880122 0.75 TGM2 (0.61) SMN1; SMN2ALDH1A1
SCHEMBL10951264 0.75 CYP1A2 (0.41) GAAMAPTMEN1KMT2ACYP1A2
SCHEMBL851567 0.74 CHKA (0.50) GAACYP1A2SMN1; SMN2ALDH1A1CHKA
SCHEMBL250420 0.74 TSHR (0.46) MEN1KMT2ANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0084692-B1 METHOD OF DISPERSING PHOTOGRAPHIC ADJUVANTS IN A HYDROPHILIC COLLOID COMPOSITION AGFA-GEVAERT N.V. (BE) 1986-06-11 EP disclosed
EP-0113484-A1 Novel 2-equivalant cyan-forming couplers and photographic elements containing them AGFA-GEVAERT N.V. (BE) 1984-07-18 EP disclosed
US-4430421-A USING IHYDROXYMETHYL(5,2,1,0(2,6))TRICYCLODECANE, OR CARBOXYLIC, PHOSPHORIC, OR PHOSPHONIC DIESTERS THEREOF AGFA-GEVAERT, N.V. (BE) 1984-02-07 US disclosed
US-4430422-A USING 1,3-DIALKYLOXY-2-PROPANOLS AND CARBOXYLIC, PHOSPHORIC OR PHOSPHONIC ESTERS THEREOF AGFA-GEVAERT, N.V. (BE) 1984-02-07 US disclosed
EP-0026520-B1 PHOTOGRAPHIC SILVER HALIDE DEVELOPMENT IN THE PRESENCE OF THIOETHER DEVELOPMENT ACTIVATORS; METHOD, DEVELOPER AND PHOTOGRAPHIC ELEMENT AGFA-GEVAERT N.V. (BE) 1983-09-14 EP disclosed
EP-0084694-A1 Method of dispersing photographic adjuvants in hydrophilic colloid compositions AGFA-GEVAERT N.V. (BE) 1983-08-03 EP disclosed
EP-0084692-A2 Method of dispersing photographic adjuvants in a hydrophilic colloid composition AGFA-GEVAERT N.V. (BE) 1983-08-03 EP disclosed
US-4292400-A Photographic silver halide development in the presence of thioether development activators AGFA-GEVAERT, N.V. (BE) 1981-09-29 US disclosed
US-4275200-A CONDENSATION OF CARBAMIC ESTERS WITH X-HALOGEN CARBONYL COMPOUNDS AGFA-GEVAERT, A.G. (DE) 1981-06-23 US disclosed
EP-0001852-B1 PHOTOGRAPHIC BLEACH COMPOSITIONS CONTAINING BLEACH-ACCELERATING COMPOUNDS AND THEIR USE IN A METHOD OF PROCESSING AN IMAGE-WISE EXPOSED PHOTOGRAPHIC SILVER HALIDE MATERIAL AGFA-GEVAERT N.V. (BE) 1981-05-20 EP disclosed
EP-0026520-A1 Photographic silver halide development in the presence of thioether development activators; method, developer and photographic element AGFA-GEVAERT N.V. (BE) 1981-04-08 EP disclosed
EP-0011092-A1 Alpha-aminophenylacetic acid derivatives for use in the treatment of inflammations and novel alpha-aminophenylacetic acid derivatives BAYER AG (DE) 1980-05-28 EP disclosed
US-4201585-A POLYOXYETHYLENE COMPOUNDS CARRYING A THIOETHER SIDECHAIN AGFA-GEVAERT, N.V. (BE) 1980-05-06 US disclosed
EP-0001852-A1 Photographic bleach compositions containing bleach-accelerating compounds and their use in a method of processing an image-wise exposed photographic silver halide material AGFA-GEVAERT N.V. (BE) 1979-05-16 EP disclosed
US-4138557-A DYE DEVELOPER AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed
US-4138263-A Photographic silver halide material with 2-equivalent, N-heterocyclic yellow couplers AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed
US-4133958-A SPLITTABLE 1,3-DIAZOLONE-2-RING AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1979-01-09 US disclosed
US-4059447-A Photographic material containing oxazolinone-2 couplers AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed
US-4049458-A KETOMETHYLENE COUPLER CONTAINING A SPLITTABLE PYRROLE, DIAZOLE OR TRIAZOLE RING ATTACHED THROUGH THE NITROGEN AGFA-GEVAERT, A.G. (DT) 1977-09-20 US disclosed
US-4046575-A COLOR PHOTOGRAPHIC MATERIAL CONTAINING 2-EQUIVALENT YELLOW COUPLERS AGFA-GEVAERT, AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed