Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692310 | 0.83 | ALDH1A1 (0.44) | MAPTHPGDRAB9ANPC1ALDH1A1 | |
| SCHEMBL11647077 | 0.82 | SYK (0.38) | MAPTHPGDRAB9ANPC1ALDH1A1 | |
| SCHEMBL11309181 | 0.81 | RAB9A (0.60) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11650930 | 0.81 | MEN1 (0.41) | MAPTHPGDRAB9ANPC1ALDH1A1 | |
| SCHEMBL1039232 | 0.79 | ALDH1A1 (0.54) | MAPTHDAC4HDAC6ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1039218 | 0.79 | ALDH1A1 (0.54) | MAPTHDAC4HDAC6ALDH1A1L3MBTL1 | |
| SCHEMBL28800706 | 0.79 | HDAC3 (0.57) | MAPTHPGDNR4A1HDAC3HDAC4 | |
| SCHEMBL28737954 | 0.79 | ALDH1A1 (0.65) | MAPTHPGDNR4A1RAB9ANPC1 | |
| SCHEMBL10184215 | 0.78 | FTO (0.50) | MAPTHPGDRAB9ANPC1ALDH1A1 | |
| SCHEMBL498570 | 0.78 | ALDH1A1 (0.54) | MAPTHPGDRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475106-A | Agonist for cholecystokinin and gastrin receptors; nervous system, gastrointestinal disorders | RHONE-POULENC RORER S.A. (FR) | 1995-12-12 | — | — | US | disclosed |