Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | BLK | P51451 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | STK3 | Q13188 | 1/20 | 0.44 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680655 | 0.80 | LYN (0.57) | IDO1KMOFYNCLK4NOTUM | |
| SCHEMBL8683290 | 0.79 | HSD11B1 (0.52) | KDM4EMAP4K4NOTUM | |
| SCHEMBL2352218 | 0.78 | AKT1 (0.52) | KDM4EMAP4K4PIM1FGFR1GSK3B | |
| SCHEMBL9822966 | 0.75 | EIF4E (0.45) | KDM4EMAP4K4 | |
| SCHEMBL23804742 | 0.75 | AKT2 (0.59) | IDO1KDM4ENOTUMCHEK1 | |
| SCHEMBL11165638 | 0.74 | KDM4E (0.54) | KDM4EMAP4K4PGRPARP10PARP11 | |
| SCHEMBL12071301 | 0.73 | LYN (0.69) | — | |
| SCHEMBL21904995 | 0.73 | BTK (0.47) | FGFR1CHEK1 | |
| SCHEMBL10898685 | 0.72 | MAP4K4 (0.50) | IDO1MAP4K4SCN2A | |
| SCHEMBL10901148 | 0.71 | CYP2A6 (0.44) | IDO1MAP4K4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613603-A | Compounds with a nitrogen-containing heterocyclic nucleus, and drugs in which they are present | SANOFI (FR) | 1986-09-23 | — | — | US | disclosed |