Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 4/20 | 0.40 |
| ▸ | MAX | P61244 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898389 | 0.83 | SMN1; SMN2 (0.41) | PIM1PIM2RAB9ANPC1LMNA | |
| SCHEMBL8958542 | 0.82 | LMNA (0.43) | PIM1PIM2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8402323 | 0.81 | ALPL (0.40) | PIM1PIM2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL10900715 | 0.81 | PIM1 (0.48) | PIM1PIM2RAB9ANPC1LMNA | |
| SCHEMBL10901430 | 0.75 | ABCC4 (0.48) | IGF1RLMNAMAPTMEN1KMT2A | |
| SCHEMBL10900026 | 0.74 | MAPT (0.47) | RAB9ANPC1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL10896573 | 0.71 | DYRK2 (0.54) | PIM1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8216537 | 0.68 | GSK3B (0.65) | IGF1RPIM1PIM2MYCMAX | |
| SCHEMBL8216533 | 0.68 | GSK3B (0.65) | IGF1RPIM1PIM2MYCMAX | |
| SCHEMBL13563893 | 0.68 | ALDH1A1 (0.61) | IGF1RPIM1PIM2MYCMAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612388-A | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1986-09-16 | — | — | US | claimed |
| US-4612388-A | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0161796-A1 | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-11-21 | — | — | EP | disclosed |