Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900715 | 0.83 | PIM1 (0.48) | ALDH1A1KMT2AMAPTMAPK1GAA | |
| SCHEMBL10898779 | 0.83 | KMT2A (0.55) | PDE4BPDE3AALDH1A1KMT2AMAPT | |
| SCHEMBL10900921 | 0.79 | CBS (0.50) | ALDH1A1KMT2AGAAKDM4EL3MBTL1 | |
| SCHEMBL10597425 | 0.75 | ABCC4 (0.55) | ABCC4ABCB11CHRM2ADRA2AADORA3 | |
| SCHEMBL10900059 | 0.74 | IGF1R (0.42) | SIRT1IGF1RALDH1A1KMT2AMAPK1 | |
| SCHEMBL10898389 | 0.73 | SMN1; SMN2 (0.41) | SIRT1ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL8958542 | 0.73 | LMNA (0.43) | SIRT1ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL10899305 | 0.72 | DYRK1A (0.54) | ACHEALDH1A1MAPTDYRK1ANPSR1 | |
| SCHEMBL10896719 | 0.72 | SIRT1 (0.48) | SIRT1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL8402323 | 0.72 | ALPL (0.40) | KMT2AMAPTHTTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612388-A | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1986-09-16 | — | — | US | claimed |
| US-4612388-A | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0161796-A1 | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-11-21 | — | — | EP | disclosed |