Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.37 |
| ▸ | RARG | P13631 | 5/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484539 | 0.83 | RARB (0.38) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9483415 | 0.80 | RARB (0.38) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9484161 | 0.79 | RXRA (0.33) | RXRA | |
| SCHEMBL1468020 | 0.66 | RXRA (0.39) | CYP3A4RXRA | |
| SCHEMBL10335841 | 0.65 | ADRA2A (0.35) | RXRA | |
| SCHEMBL9484739 | 0.62 | RXRA (0.59) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6435749 | 0.62 | HTR2A (0.37) | RXRA | |
| SCHEMBL16318604 | 0.60 | RXRA (0.47) | RXRA | |
| SCHEMBL10963336 | 0.60 | POLB (0.36) | RXRA | |
| SCHEMBL10841013 | 0.59 | GABRA1 (0.41) | RARBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0176034-A2 | Diaryl acetylenes, their preparation and use | BASF Aktiengesellschaft (DE) | 1986-04-02 | — | — | EP | disclosed |