Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898759 | 0.84 | AKR1B1 (0.51) | AKR1B1MMP3MMP13SIRT1PARP1 | |
| SCHEMBL8958542 | 0.83 | LMNA (0.43) | SIRT1ALPI | |
| SCHEMBL10897268 | 0.76 | KMT2A (0.44) | PTGS2 | |
| SCHEMBL8170053 | 0.75 | RXRA (0.45) | AKR1B1MMP3MMP13ADAMTS5 | |
| SCHEMBL10730264 | 0.74 | AKR1B1 (0.49) | AKR1B1MMP3MMP13PARP1TLR4 | |
| SCHEMBL10899305 | 0.73 | DYRK1A (0.54) | AKR1B1PSMB5ALPI | |
| SCHEMBL10898779 | 0.73 | KMT2A (0.55) | PSMB5 | |
| SCHEMBL8961052 | 0.73 | NOTUM (0.39) | SIRT1 | |
| SCHEMBL8961053 | 0.73 | NOTUM (0.39) | SIRT1 | |
| SCHEMBL10900059 | 0.72 | IGF1R (0.42) | SIRT1ADAMTS5PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612388-A | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1986-09-16 | — | — | US | claimed |
| US-4612388-A | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0161796-A1 | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-11-21 | — | — | EP | disclosed |