Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.48 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901430 | 0.83 | ABCC4 (0.48) | KMT2AMAPTLMNAGAAMAPK1 | |
| SCHEMBL10900921 | 0.82 | CBS (0.50) | KMT2AGAAALDH1A1KDM4ERAB9A | |
| SCHEMBL10899305 | 0.81 | DYRK1A (0.54) | MAPTPSMB5PIM1PIM2ALDH1A1 | |
| SCHEMBL10897268 | 0.78 | KMT2A (0.44) | KMT2AMAPTNCOA3KDM4EMEN1 | |
| SCHEMBL10900059 | 0.77 | IGF1R (0.42) | KMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL10898389 | 0.76 | SMN1; SMN2 (0.41) | KMT2AMAPTLMNATDP1PIM1 | |
| SCHEMBL10896719 | 0.75 | SIRT1 (0.48) | MAPTGAAPIM1PIM2ALDH1A1 | |
| SCHEMBL8402323 | 0.75 | ALPL (0.40) | KMT2AMAPTLMNATDP1PIM1 | |
| SCHEMBL7990683 | 0.74 | KMT2A (0.54) | KMT2AMAPTLMNAPLIN1GAA | |
| SCHEMBL10896573 | 0.74 | DYRK2 (0.54) | KMT2AMAPTLMNAMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612388-A | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1986-09-16 | — | — | US | claimed |
| US-4612388-A | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0161796-A1 | Process for producing N-acylphenylalanines | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-11-21 | — | — | EP | disclosed |