Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | PRF1 | P14222 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961052 | 1.00 | NOTUM (0.39) | NOTUMBRD4CREBBPPRF1HTR7 | |
| SCHEMBL8958542 | 0.76 | LMNA (0.43) | MEN1KMT2ASIRT1LMNAKDM4E | |
| SCHEMBL10898389 | 0.73 | SMN1; SMN2 (0.41) | BRD4CREBBPPOLBMEN1KMT2A | |
| SCHEMBL10899448 | 0.73 | AKR1B1 (0.48) | SIRT1 | |
| SCHEMBL5734465 | 0.69 | TRIM24 (0.54) | NOTUMBRD4HTR7ELANELMNA | |
| SCHEMBL8402323 | 0.69 | ALPL (0.40) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL10896573 | 0.68 | DYRK2 (0.54) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL9297456 | 0.68 | NOTUM (0.55) | NOTUMELANEPOLBGAABACE1 | |
| SCHEMBL10901430 | 0.67 | ABCC4 (0.48) | POLBGAAMEN1KMT2ASIRT1 | |
| SCHEMBL5396176 | 0.64 | HTR7 (0.52) | HTR7MEN1KMT2ABACE1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546387-B1 | Substituted oximetheramides | BAYER AG (DE) | 1996-01-31 | — | — | EP | disclosed |
| EP-0546387-A1 | Substituted oximetheramides | BAYER AG (DE) | 1993-06-16 | — | — | EP | disclosed |