Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899544 | 0.82 | L3MBTL1 (0.50) | L3MBTL1RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL10901859 | 0.77 | CHRM2 (0.52) | L3MBTL1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL10899596 | 0.76 | KDM4E (0.63) | L3MBTL1RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL16242688 | 0.74 | L3MBTL1 (0.41) | L3MBTL1RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL16242876 | 0.73 | SMN1; SMN2 (0.48) | RAB9AALDH1A1KDM4EGAAGLA | |
| SCHEMBL6871964 | 0.71 | SIGMAR1 (0.47) | L3MBTL1GAA | |
| SCHEMBL4705226 | 0.71 | GAA (0.58) | L3MBTL1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL4055416 | 0.71 | ALDH1A1 (0.71) | ALDH1A1KDM4EGAAKMT2ABRD4 | |
| SCHEMBL10899838 | 0.71 | CCR6 (0.44) | L3MBTL1ALDH1A1KDM4EGAAUSP2 | |
| SCHEMBL10902963 | 0.71 | KDM4E (0.44) | L3MBTL1ALDH1A1KDM4EGAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |