Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584970 | 0.85 | NQO2 (0.39) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL22991357 | 0.77 | MEN1 (0.42) | KDM4EALDH1A1MAPTHPGDCA5A | |
| SCHEMBL23511720 | 0.75 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL22560905 | 0.73 | CA12 (0.41) | KDM4EALDH1A1MAPTHPGDNQO2 | |
| SCHEMBL2222259 | 0.73 | SIRT3 (0.39) | KDM4EALDH1A1NQO2CDC7MKNK1 | |
| SCHEMBL31493862 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL27902963 | 0.72 | NQO2 (0.40) | KDM4EALDH1A1MAPTHPGDTSHR | |
| Water SCHEMBL28292285 | 0.72 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL70150 | 0.71 | TTR (0.42) | KDM4EALDH1A1HPGDHSD17B10LCK | |
| SCHEMBL11052232 | 0.70 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563305-A | QUANTITATIVE ANALYSIS | UNIVERSITY OF MIAMI (US) | 1986-01-07 | — | — | US | disclosed |
| EP-0056015-A1 | Radiolabelled substrates for assaying mammalian enzymes | Ryan, James Walter (US) | 1982-07-14 | — | — | EP | disclosed |