Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28218019 | 0.80 | HDAC4 (0.50) | KDM4ELMNAHDAC4HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL28792527 | 0.78 | CYP2A6 (0.42) | KDM4ELMNACYP3A4HSD17B10HPGD | |
| SCHEMBL31265929 | 0.78 | LMNA (0.44) | KDM4ELMNAHDAC4HDAC2HDAC8 | |
| SCHEMBL31265998 | 0.76 | MAOA (0.44) | KDM4ELMNAMEN1CYP3A4KMT2A | |
| SCHEMBL8658066 | 0.74 | MEN1 (0.45) | KDM4ELMNAHDAC4HDAC2HDAC8 | |
| SCHEMBL31265959 | 0.72 | CYP1A1 (0.50) | KDM4ELMNAMEN1CYP3A4KMT2A | |
| SCHEMBL14901086 | 0.69 | ALDH1A1 (0.46) | KDM4EKMT2AHPGDALDH1A1ALOX15 | |
| SCHEMBL10943763 | 0.69 | — | — | |
| SCHEMBL22597348 | 0.69 | MEN1 (0.43) | KDM4ELMNAHDAC6MEN1CYP3A4 | |
| SCHEMBL29390675 | 0.68 | BACE1 (0.41) | KDM4ELMNAHDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608367-A | γ-Pyrone phosphoric ester derivatives and insecticidal and miticidal compositions thereof | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1986-08-26 | — | — | US | disclosed |