SCHEMBL109003

SCHEMBL109003

Nc1ccc(S(=O)(=O)F)c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.50
IDO1 P14902 2/20 0.43
HDAC3 O15379 1/20 0.43
EP300 Q09472 1/20 0.43
KAT2B Q92831 1/20 0.43
KAT8 Q9H7Z6 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
NSD2 O96028 8/20 0.43
ELANE P08246 1/20 0.42
LDHA P00338 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GAA P10253 1/20 0.40
AURKA O14965 1/20 0.40
AURKB Q96GD4 1/20 0.40
CHEK1 O14757 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11575541 0.87 ELANE (0.46) TTRELANELDHAALDH1A1TSHR
SCHEMBL108422 0.81 LDHA (0.64) TTRIDO1HDAC3EP300KAT2B
SCHEMBL636440 0.79 TTR (0.50) TTRIDO1HDAC3EP300KAT2B
SCHEMBL38143 0.79 TTR (0.50) TTRIDO1HDAC3EP300KAT2B
SCHEMBL150853 0.79 TTR (0.78) TTRIDO1HDAC3EP300KAT2B
SCHEMBL29516385 0.79 TTR (0.78) TTRIDO1HDAC3EP300KAT2B
SCHEMBL19922628 0.79 TTR (0.50) TTRIDO1HDAC3EP300KAT2B
SCHEMBL10730555 0.79 TTR (0.50) TTRIDO1HDAC3EP300KAT2B
SCHEMBL1525888 0.79 TTR (0.78) TTRIDO1HDAC3EP300KAT2B
SCHEMBL31603821 0.79 TTR (0.50) TTRIDO1HDAC3EP300KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1004 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117790902-A Electrolyte containing sulfonyl fluoride compound and lithium ion battery containing electrolyte 湖州昆仑亿恩科电池材料有限公司 2024-03-29 CN claimed
WO-2023164252-A1 ISOTHERMAL NUCLEIC ACID DETECTION ASSAYS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-08-31 WO claimed
CN-109342381-A A kind of fluorescent dyeing reagent 广州往圣生物科技有限公司 2019-02-15 CN claimed
US-9915665-B2 High-throughput system and method for identifying antibodies having specific antigen binding activities ABBVIE INC. (US) 2018-03-13 US claimed
EP-2938636-A2 HIGH-THROUGHPUT SYSTEM AND METHOD FOR IDENTIFYING ANTIBODIES HAVING SPECIFIC ANTIGEN BINDING ACTIVITIES AbbVie Inc. (US) 2015-11-04 EP claimed
US-20140243228-A1 HIGH-THROUGHPUT SYSTEM AND METHOD FOR IDENTIFYING ANTIBODIES HAVING SPECIFIC ANTIGEN BINDING ACTIVITIES ABBVIE, INC. (US) 2014-08-28 US claimed
WO-2014106004-A2 HIGH-THROUGHPUT SYSTEM AND METHOD FOR IDENTIFYING ANTIBODIES HAVING SPECIFIC ANTIGEN BINDING ACTIVITIES ABBVIE, INC. (US) 2014-07-03 WO claimed
WO-2013070943-A2 SMALL MOLECULE SCREEN FOR INHIBITORS OF NFAT:AP-1:DNA INTERACTIONS CHILDREN'S MEDICAL CENTER CORPORATION (US) 2013-05-16 WO claimed
WO-2009018368-A1 COMBINATION TREATMENT OF NMDA (N-METHYL-D-ASPARTATE)-ENHANCER, GLYCINE TRANSPORTER INHIBITOR, D-AMINO ACID OXIDASE INHIBITOR (DAAOI) FOR NEUROPSYCHIATRIC DISORDERS LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) 2009-02-05 WO claimed
US-20080315084-A1 ANALYSIS METHOD OF AMINO ACID USING MASS SPECTROMETER AJINOMOTO CO. INC (JP) 2008-12-25 US claimed
EP-1965205-A1 AMINO ACID ANALYSIS METHOD USING MASS SPECTROMETER Ajinomoto Co., Inc. (JP) 2008-09-03 EP claimed
US-5110746-A Method for the determination of albumin in biological fluids PHARMACIA DIAGNOSTICS INC. (US) 1992-05-05 US claimed
EP-0287745-B1 METHOD FOR THE DETERMINATION OF ALBUMIN IN BIOLOGICAL FLUIDS SCHIAPPARELLI BIOSYSTEMS, INC. (US) 1991-11-13 EP claimed
WO-1988008533-A1 METHOD FOR THE DETERMINATION OF ALBUMIN IN BIOLOGICAL FLUIDS ELECTRO-NUCLEONICS, INC. (US) 1988-11-03 WO claimed
EP-0287745-A1 Method for the determination of albumin in biological fluids SCHIAPPARELLI BIOSYSTEMS, INC. (US) 1988-10-26 EP claimed
WO-2026107198-A1 ANTIBODY BIOMARKER TO DIAGNOSE IDIOPATHIC INFLAMMATORY MYOPATHIES OHIO STATE INNOVATION FOUNDATION (US) 2026-05-21 WO disclosed
US-20260125675-A1 DOWNREGULATING TROLLS USING NOVEL ANTISENSE OLIGONUCLEOTIDES TO OVERCOME RESISTANCE TO CHEMOTHERAPY H LEE MOFFITT CANCER CENTER AND RESEARCH INST INC (US) 2026-05-07 US disclosed
EP-0287745-B1 METHOD FOR THE DETERMINATION OF ALBUMIN IN BIOLOGICAL FLUIDS SCHIAPPARELLI BIOSYSTEMS, INC. (US) 1991-11-13 EP disclosed
WO-1988008533-A1 METHOD FOR THE DETERMINATION OF ALBUMIN IN BIOLOGICAL FLUIDS ELECTRO-NUCLEONICS, INC. (US) 1988-11-03 WO disclosed
EP-0287745-A1 Method for the determination of albumin in biological fluids SCHIAPPARELLI BIOSYSTEMS, INC. (US) 1988-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125675-A1 DOWNREGULATING TROLLS USING NOVEL ANTISENSE OLIGONUCLEOTIDES TO OVERCOME RESISTANCE TO CHEMOTHERAPY PDCD1LG2, TRMT1L, TTLL12 TTR 3670/4885IDO1 3541/4885HDAC3 2144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.