Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | ME2 | P23368 | 1/20 | 0.64 |
| ▸ | ME1 | P48163 | 1/20 | 0.64 |
| ▸ | ME3 | Q16798 | 1/20 | 0.64 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901064 | 0.92 | ITGB3 (0.70) | GFERATMME2ME1ME3 | |
| SCHEMBL10900735 | 0.89 | ADRA1D (0.59) | GFERATMME2ME1ME3 | |
| SCHEMBL10901774 | 0.89 | LMNA (0.70) | GFERATMME2ME1ME3 | |
| SCHEMBL1065084 | 0.84 | ITGB3 (0.64) | ITGB3ITGA2BMEN1KMT2AMAPT | |
| SCHEMBL2285282 | 0.84 | ITGB3 (0.64) | ME2ME1ME3ITGB3ITGA2B | |
| SCHEMBL10897475 | 0.83 | MEN1 (0.68) | GFERATMME2ME1ME3 | |
| SCHEMBL10898228 | 0.83 | MEN1 (0.60) | GFERATMME2ME1ME3 | |
| SCHEMBL10900952 | 0.83 | EBP (0.58) | GFERATMME2ME1ME3 | |
| SCHEMBL10898221 | 0.83 | MEN1 (0.60) | GFERATMME2ME1ME3 | |
| SCHEMBL10900946 | 0.83 | EBP (0.58) | GFERATMME2ME1ME3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0076996-A1 | Carboxylic-acid derivatives, process for their preparation and medicines containing them | Roche Diagnostics GmbH (DE) | 1983-04-20 | — | — | EP | disclosed |