Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | ME2 | P23368 | 1/20 | 0.60 |
| ▸ | ME1 | P48163 | 1/20 | 0.60 |
| ▸ | ME3 | Q16798 | 1/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900400 | 0.89 | GFER (0.66) | LMNAALDH1A1AKR1C3GFERATM | |
| SCHEMBL24158074 | 0.87 | LMNA (0.85) | LMNAALDH1A1HSP90AA1AKR1C3MEN1 | |
| SCHEMBL10900891 | 0.87 | LMNA (0.67) | LMNAALDH1A1HSP90AA1AKR1C3GFER | |
| SCHEMBL6705171 | 0.83 | LMNA (0.88) | LMNAALDH1A1HSP90AA1AKR1C3MEN1 | |
| SCHEMBL10901064 | 0.82 | ITGB3 (0.70) | ALDH1A1GFERATMME2ME1 | |
| SCHEMBL10901628 | 0.82 | THRB (0.71) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10902216 | 0.81 | GFER (0.78) | LMNAALDH1A1AKR1C3GFERATM | |
| SCHEMBL9321490 | 0.80 | LMNA (0.74) | LMNAALDH1A1HSP90AA1AKR1C3GFER | |
| SCHEMBL13972823 | 0.80 | LMNA (0.64) | LMNAALDH1A1HSP90AA1AKR1C3MEN1 | |
| SCHEMBL9011009 | 0.80 | LMNA (0.76) | LMNAALDH1A1ITGB3ITGA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0076996-A1 | Carboxylic-acid derivatives, process for their preparation and medicines containing them | Roche Diagnostics GmbH (DE) | 1983-04-20 | — | — | EP | disclosed |