Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1577063 | 0.80 | NOS2 (0.52) | HSP90AB1HSP90AA1NUDT1NOS1NOS2 | |
| SCHEMBL15306037 | 0.78 | NUDT1 (0.45) | HSP90AB1HSP90AA1NUDT1NOS1NOS2 | |
| SCHEMBL14730003 | 0.78 | HSP90AB1 (0.44) | HSP90AB1HSP90AA1NUDT1NOS1NOS2 | |
| SCHEMBL8364061 | 0.77 | NOS2 (0.55) | HSP90AB1HSP90AA1NUDT1NOS1NOS2 | |
| SCHEMBL10618268 | 0.76 | SMN1; SMN2 (0.40) | HSP90AB1HRH4SMN1; SMN2 | |
| SCHEMBL151114 | 0.75 | — | — | |
| SCHEMBL11596162 | 0.75 | NOS2 (0.56) | HSP90AB1HSP90AA1NUDT1NOS1NOS2 | |
| SCHEMBL10619523 | 0.74 | HSP90AB1 (0.56) | HSP90AB1HSP90AA1HRH4SMN1; SMN2CYP1A2 | |
| SCHEMBL10617499 | 0.74 | ALDH1A1 (0.46) | HSP90AB1HSP90AA1NUDT1HRH4POLB | |
| SCHEMBL10620437 | 0.74 | HRH4 (0.38) | HSP90AB1HSP90AA1HRH4TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563211-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-07 | — | — | US | disclosed |