Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.53 |
| ▸ | SOD1 | P00441 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899677 | 0.89 | KCNJ1 (0.65) | KCNJ1KCNH2ALDH1A1TSHRMAPT | |
| SCHEMBL10899492 | 0.86 | THRB (0.65) | KCNJ1KCNH2ALDH1A1TSHRMAPT | |
| SCHEMBL8205972 | 0.85 | ALDH1A1 (0.58) | KCNJ1KCNH2SOD1ALDH1A1TSHR | |
| SCHEMBL10902040 | 0.84 | KCNJ1 (0.57) | KCNJ1KCNH2ADRA1DADRA1AADRA1B | |
| SCHEMBL10900781 | 0.84 | KCNJ1 (0.59) | KCNJ1KCNH2ALDH1A1TSHRMAPT | |
| SCHEMBL10901601 | 0.84 | ADRA1D (0.68) | ADRA1DADRA1AADRA1BSOD1SMN1; SMN2 | |
| SCHEMBL10901296 | 0.83 | KMT2A (0.70) | SOD1ALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL10902081 | 0.83 | SIGMAR1 (0.65) | ADRA1DADRA1AADRA1BSOD1HTR1A | |
| SCHEMBL10901022 | 0.82 | CYP2C9 (0.66) | KCNJ1KCNH2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10899620 | 0.82 | KCNH2 (0.57) | KCNJ1KCNH2ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |