Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 5/20 | 0.33 |
| ▸ | PPARD | Q03181 | 5/20 | 0.33 |
| ▸ | PPARA | Q07869 | 5/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28206312 | 0.81 | EPHX2 (0.42) | ABCC4MAPTLMNASLC22A6PHF8 | |
| SCHEMBL3278967 | 0.81 | ZDHHC20 (0.44) | TSHREPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL24089401 | 0.78 | MAPT (0.36) | MAPTTSHRALDH1A1 | |
| SCHEMBL17049103 | 0.78 | ZDHHC20 (0.53) | TSHREPHX2MEN1KMT2A | |
| SCHEMBL10905757 | 0.77 | AKR1B1 (0.46) | SLC22A6PHF8KDM2ATSHRAKR1B1 | |
| SCHEMBL10903601 | 0.77 | CAMK2A (0.44) | LMNASLC22A6PHF8KDM2ATSHR | |
| SCHEMBL137211 | 0.76 | ZDHHC20 (0.39) | TSHRALDH1A1 | |
| SCHEMBL10903599 | 0.76 | LMNA (0.42) | LMNASLC22A6PHF8KDM2ATSHR | |
| SCHEMBL18229077 | 0.76 | EPHX2 (0.49) | ABCC4MAPTLMNASLC22A6PHF8 | |
| SCHEMBL10903614 | 0.75 | LMNA (0.40) | LMNASLC22A6PHF8KDM2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |