Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 9/20 | 0.37 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905757 | 0.84 | AKR1B1 (0.46) | PHF8KDM2AGPR84FFAR1FFAR4 | |
| SCHEMBL10906605 | 0.81 | AKR1B1 (0.59) | PHF8GPR84FFAR1FFAR4KDM4C | |
| SCHEMBL10905768 | 0.79 | GPR84 (0.61) | PHF8GPR84FFAR1FFAR4KDM4C | |
| SCHEMBL10907491 | 0.79 | GPR84 (0.61) | PHF8GPR84FFAR1FFAR4KDM4C | |
| SCHEMBL10903599 | 0.79 | LMNA (0.42) | PHF8KDM2AGPR84FFAR1FFAR4 | |
| SCHEMBL10903614 | 0.78 | LMNA (0.40) | PHF8KDM2AGPR84FFAR1FFAR4 | |
| SCHEMBL10905695 | 0.77 | AKR1B1 (0.59) | PHF8GPR84FFAR1FFAR4KDM4C | |
| SCHEMBL10903589 | 0.77 | ABCC4 (0.38) | PHF8KDM2AGPR84FFAR1FFAR4 | |
| SCHEMBL10907490 | 0.74 | LMNA (0.37) | PHF8KDM2AGPR84FFAR1FFAR4 | |
| SCHEMBL10906197 | 0.74 | KDM4C (0.38) | PHF8KDM2AKDM4CLMNAKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |