Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PPARD | Q03181 | 7/20 | 0.45 |
| ▸ | PPARA | Q07869 | 7/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906605 | 0.89 | AKR1B1 (0.59) | AKR1B1KDM5AKDM4CGPR84PPARG | |
| SCHEMBL10905768 | 0.87 | GPR84 (0.61) | AKR1B1KDM5AKDM4CGPR84PPARG | |
| SCHEMBL10907491 | 0.87 | GPR84 (0.61) | AKR1B1KDM5AKDM4CGPR84PPARG | |
| SCHEMBL10905695 | 0.85 | AKR1B1 (0.59) | AKR1B1KDM5AKDM4CGPR84PPARG | |
| SCHEMBL10903601 | 0.84 | CAMK2A (0.44) | AKR1B1KDM5AKDM4CGPR84TSHR | |
| SCHEMBL10903599 | 0.79 | LMNA (0.42) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL10903614 | 0.78 | LMNA (0.40) | AKR1B1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10903589 | 0.77 | ABCC4 (0.38) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL1310513 | 0.76 | GPR84 (0.50) | AKR1B1KDM5AKDM4CGPR84PPARG | |
| SCHEMBL1309401 | 0.76 | GPR84 (0.50) | AKR1B1KDM5AKDM4CGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |