Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CBX7 | O95931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340257 | 0.93 | TIMP3 (0.58) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL10908211 | 0.91 | MEN1 (0.53) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL10905184 | 0.91 | KMT2A (0.47) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL10905294 | 0.87 | CASP6 (0.55) | KMT2ATIMP3APEX1CASP6CTDSP1 | |
| SCHEMBL11439331 | 0.85 | CASP6 (0.50) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL11761158 | 0.85 | TIMP3 (0.61) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL11337363 | 0.84 | TIMP3 (0.61) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL11342887 | 0.84 | TIMP3 (0.55) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL11761109 | 0.84 | TIMP3 (0.60) | MEN1KMT2ATIMP3USP2RECQL | |
| SCHEMBL10909338 | 0.83 | CASP6 (0.67) | MEN1KMT2ATIMP3USP2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |