Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.47 |
| ▸ | FGF1 | P05230 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352224 | 0.93 | PRMT1 (0.57) | CASP6CTDSP1APEX1PRMT1TIMP3 | |
| SCHEMBL10905209 | 0.91 | ENPP2 (0.51) | CASP6CTDSP1APEX1PRMT1TIMP3 | |
| SCHEMBL10905485 | 0.87 | MEN1 (0.50) | CASP6CTDSP1APEX1PRMT1TIMP3 | |
| SCHEMBL11426265 | 0.87 | CASP6 (0.65) | CASP6CTDSP1APEX1PRMT1TIMP3 | |
| SCHEMBL10905168 | 0.84 | MEN1 (0.46) | CASP6CTDSP1APEX1PRMT1TIMP3 | |
| SCHEMBL11350067 | 0.83 | TIMP3 (0.57) | CASP6CTDSP1APEX1PRMT1TIMP3 | |
| SCHEMBL10908562 | 0.83 | PRMT1 (0.46) | CASP6CTDSP1APEX1PRMT1TIMP3 | |
| SCHEMBL11431125 | 0.83 | MAPT (0.57) | CASP6CTDSP1APEX1CA2CA1 | |
| SCHEMBL10907433 | 0.81 | CASP6 (0.80) | CASP6CTDSP1APEX1PRMT1TIMP3 | |
| SCHEMBL11340257 | 0.81 | TIMP3 (0.58) | CASP6CTDSP1APEX1PRMT1TIMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |