Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11763835 | 0.92 | APEX1 (0.53) | CASP6CTDSP1APEX1HSD17B10SMN1; SMN2 | |
| SCHEMBL11426066 | 0.91 | APEX1 (0.50) | CASP6CTDSP1APEX1HSD17B10SMN1; SMN2 | |
| SCHEMBL11434078 | 0.91 | CASP6 (0.50) | CASP6CTDSP1APEX1HSD17B10SMN1; SMN2 | |
| SCHEMBL11426265 | 0.87 | CASP6 (0.65) | CASP6CTDSP1APEX1HSD17B10SMN1; SMN2 | |
| SCHEMBL10905485 | 0.85 | MEN1 (0.50) | CASP6CTDSP1APEX1HSD17B10NSD2 | |
| SCHEMBL11340257 | 0.85 | TIMP3 (0.58) | CASP6CTDSP1APEX1HSD17B10NSD2 | |
| SCHEMBL11430180 | 0.83 | RAB9A (0.54) | CTDSP1APEX1SMN1; SMN2DUSP3PTPN5 | |
| SCHEMBL11427527 | 0.82 | CASP6 (0.48) | CASP6CTDSP1APEX1HSD17B10SMN1; SMN2 | |
| SCHEMBL11433965 | 0.82 | CASP6 (0.48) | CASP6CTDSP1APEX1HSD17B10NSD2 | |
| SCHEMBL5567709 | 0.81 | APEX1 (0.76) | CASP6CTDSP1APEX1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |