Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561049 | 0.93 | CTRB1 (0.55) | ALDH1A1CTRB1ATMNPC1RAB9A | |
| SCHEMBL9141456 | 0.93 | ALDH1A1 (0.56) | ALDH1A1ALOX15CTRB1ATMNPC1 | |
| SCHEMBL28314849 | 0.93 | ALDH1A1 (0.56) | ALDH1A1ALOX15CTRB1ATMNPC1 | |
| SCHEMBL8561874 | 0.90 | CTRB1 (0.56) | CTRB1ATMNPC1RAB9AHSD17B10 | |
| SCHEMBL20299914 | 0.88 | ALDH1A1 (0.62) | ALDH1A1ALOX15CTRB1ATMMEN1 | |
| SCHEMBL17034708 | 0.88 | ALDH1A1 (0.62) | ALDH1A1ALOX15CTRB1ATMMEN1 | |
| SCHEMBL9192816 | 0.87 | CTRB1 (0.58) | ALDH1A1ALOX15CTRB1ATMNPC1 | |
| SCHEMBL18334515 | 0.87 | CTRB1 (0.58) | ALDH1A1ALOX15CTRB1ATMNPC1 | |
| SCHEMBL10787497 | 0.83 | CTRB1 (0.60) | ALDH1A1CTRB1ATMNPC1RAB9A | |
| SCHEMBL2949040 | 0.82 | CTSK (0.57) | CTRB1ATMNPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593118-A | 2-amido-3-aminocarboxylic acid esters and process of preparation thereof | ETHYL CORPORATION (US) | 1986-06-03 | — | — | US | disclosed |