Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907616 | 0.80 | KMT2A (0.44) | HSD11B1KMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL9557540 | 0.75 | HSD11B1 (0.42) | HSD11B1KMT2AMEN1TRPM8MLYCD | |
| SCHEMBL9557948 | 0.74 | HSD11B1 (0.49) | HSD11B1KMT2AMEN1TRPM8MLYCD | |
| SCHEMBL10906611 | 0.73 | KMT2A (0.44) | HSD11B1KMT2ATRPM8HDAC1HDAC6 | |
| SCHEMBL11238921 | 0.72 | PGR (0.46) | HSD11B1KMT2AMEN1TRPM8MLYCD | |
| SCHEMBL28307954 | 0.72 | PGR (0.46) | HSD11B1KMT2AMEN1TRPM8MLYCD | |
| SCHEMBL11238917 | 0.72 | PGR (0.46) | HSD11B1KMT2AMEN1TRPM8MLYCD | |
| SCHEMBL13306912 | 0.71 | KMT2A (0.47) | HSD11B1KMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL394512 | 0.71 | HSD11B1 (0.53) | HSD11B1KMT2ATRPM8MLYCDHPGD | |
| SCHEMBL1003650 | 0.70 | NAMPT (0.55) | HSD11B1KMT2AMEN1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |