Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906601 | 0.76 | GAA (0.49) | LMNANPC1RAB9AHPGDGAA | |
| SCHEMBL10906588 | 0.74 | GABRP (0.43) | LMNACYP1A2CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL10906191 | 0.73 | HSD11B1 (0.42) | KMT2ALMNANPC1MAPTRAB9A | |
| SCHEMBL28129663 | 0.73 | FOLH1 (0.47) | KMT2ANR4A2TDP1LMNAHSD17B10 | |
| SCHEMBL28129661 | 0.73 | FOLH1 (0.47) | KMT2ANR4A2TDP1LMNAHSD17B10 | |
| SCHEMBL9210808 | 0.72 | ALDH1A1 (0.42) | KMT2ANR4A2TDP1LMNAHSD17B10 | |
| SCHEMBL10906180 | 0.71 | GABRP (0.41) | CYP1A2CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL9557591 | 0.71 | ALDH1A1 (0.44) | KMT2ALMNAMAPTRAB9AATM | |
| SCHEMBL31170383 | 0.71 | ADRA2B (0.59) | KMT2ANPC1RAB9AATMALDH1A1 | |
| SCHEMBL27805530 | 0.71 | TRPM8 (0.44) | KMT2ANR4A2TDP1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |