Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906191 | 0.80 | HSD11B1 (0.42) | KMT2AMEN1NPSR1KDM4EHDAC1 | |
| SCHEMBL11255341 | 0.73 | KMT2A (0.58) | KMT2AHTTMEN1PLA2G1BNPSR1 | |
| SCHEMBL11255339 | 0.73 | KMT2A (0.58) | KMT2AHTTMEN1PLA2G1BNPSR1 | |
| SCHEMBL12983654 | 0.68 | KMT2A (0.56) | KMT2AHTTMEN1PLA2G1BNPSR1 | |
| SCHEMBL6499535 | 0.68 | HDAC1 (0.47) | KMT2AHTTMEN1PLA2G1BNPSR1 | |
| SCHEMBL10907611 | 0.68 | MAOB (0.46) | KMT2AMEN1TSHRHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL6499537 | 0.67 | HDAC1 (0.46) | KMT2AHTTMEN1PLA2G1BNPSR1 | |
| SCHEMBL9557948 | 0.66 | HSD11B1 (0.49) | KMT2AHTTMEN1NPSR1KDM4E | |
| SCHEMBL28718389 | 0.66 | TSHR (0.42) | KMT2AHTTMEN1PLA2G1BNPSR1 | |
| SCHEMBL10906611 | 0.66 | KMT2A (0.44) | KMT2AHTTTSHRKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |