Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 3/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903602 | 0.79 | HDAC3 (0.47) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL1231956 | 0.75 | MAPT (0.56) | ALOX5HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL10905465 | 0.75 | LTA4H (0.50) | ATMMAPT | |
| SCHEMBL2676817 | 0.75 | KDM4A (0.67) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL10906612 | 0.74 | HDAC6 (0.50) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| Hydrochloric Acid SCHEMBL8891865 | 0.73 | KDM4A (0.68) | SMN1; SMN2KDM4AKDM4C | |
| SCHEMBL15477428 | 0.73 | CES2 (0.52) | ALOX5HDAC8HDAC6AKR1B1LTB4R | |
| SCHEMBL339507 | 0.73 | CES2 (0.56) | ALOX5HDAC8HDAC6AKR1B1LTB4R | |
| Adipic Acid SCHEMBL5506667 | 0.73 | AKR1B1 (0.77) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9554752 | 0.72 | SIGMAR1 (0.62) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |