Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906136 | 0.85 | LTA4H (0.45) | LTA4HALDH1A1L3MBTL1PPARAICMT | |
| SCHEMBL10906603 | 0.81 | LTA4H (0.46) | LTA4HL3MBTL1PPARAICMTALB | |
| SCHEMBL10903651 | 0.78 | USP2 (0.63) | MEN1KMT2AMTORALDH1A1NPSR1 | |
| SCHEMBL10903602 | 0.76 | HDAC3 (0.47) | KMT2AALDH1A1PPARAMAPT | |
| SCHEMBL10906197 | 0.75 | KDM4C (0.38) | — | |
| SCHEMBL10906193 | 0.75 | ALOX5 (0.51) | ATMMAPT | |
| SCHEMBL17342609 | 0.74 | MTOR (0.59) | LTA4HMEN1KMT2AMTORALDH1A1 | |
| SCHEMBL10905471 | 0.73 | MTOR (0.51) | MEN1KMT2AMTORALDH1A1NPSR1 | |
| SCHEMBL10906612 | 0.72 | HDAC6 (0.50) | KMT2AL3MBTL1PPARAMAPT | |
| SCHEMBL30786401 | 0.72 | ICMT (0.71) | LTA4HMEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |