Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906183 | 0.74 | MAPT (0.40) | GAAALDH1A1MAPTSMN1; SMN2FAAH | |
| SCHEMBL10906623 | 0.72 | GAA (0.37) | GAAALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL10903598 | 0.72 | TSHR (0.42) | GAAALDH1A1MAPTSMN1; SMN2FAAH | |
| SCHEMBL10906624 | 0.71 | GAA (0.38) | GAAALPLALDH1A1ATMMAPT | |
| SCHEMBL5892318 | 0.68 | MAPK1 (0.48) | ATMMAPTSMN1; SMN2HTTKMT2A | |
| SCHEMBL10903591 | 0.68 | SLC1A3 (0.44) | KMT2ATSHRUSP2 | |
| SCHEMBL28162306 | 0.67 | CA2 (0.41) | ALDH1A1MAPTKMT2AFAAHTSHR | |
| SCHEMBL10906616 | 0.67 | ALDH1A1 (0.37) | GAAALDH1A1HPGDKMT2ATSHR | |
| SCHEMBL9555565 | 0.66 | — | — | |
| SCHEMBL22769175 | 0.66 | ALDH1A1 (0.50) | GAAALDH1A1MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |