Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 11/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906183 | 0.95 | MAPT (0.40) | TSHRSMN1; SMN2FAAHMAPTABCC4 | |
| SCHEMBL10907540 | 0.74 | ALDH1A1 (0.36) | TSHRKDM4AKDM4CKDM5AKDM7A | |
| SCHEMBL10906603 | 0.74 | LTA4H (0.46) | MAPTGAAKDM4AKDM4C | |
| SCHEMBL10906623 | 0.73 | GAA (0.37) | TSHRSMN1; SMN2FAAHMAPTGAA | |
| SCHEMBL10906622 | 0.72 | GAA (0.36) | TSHRSMN1; SMN2FAAHMAPTGAA | |
| SCHEMBL10903597 | 0.71 | GAA (0.35) | TSHRSMN1; SMN2FAAHMAPTGAA | |
| SCHEMBL10906616 | 0.71 | ALDH1A1 (0.37) | TSHRGAAALDH1A1 | |
| SCHEMBL6881087 | 0.70 | TSHR (0.83) | TSHRSMN1; SMN2FAAHMAPTABCC4 | |
| SCHEMBL10906590 | 0.70 | LMNA (0.46) | TSHRKDM4AKDM4CKDM5AKDM7A | |
| SCHEMBL10906136 | 0.70 | LTA4H (0.45) | MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |