Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906183 | 0.72 | MAPT (0.40) | ALDH1A1GAATSHRL3MBTL1 | |
| SCHEMBL10903598 | 0.71 | TSHR (0.42) | ALDH1A1GAATSHR | |
| SCHEMBL10905605 | 0.71 | LMNA (0.59) | ALDH1A1GAALMNAKMT2AHPGD | |
| SCHEMBL22769175 | 0.70 | ALDH1A1 (0.50) | ALDH1A1GAATSHRKMT2AL3MBTL1 | |
| SCHEMBL9555565 | 0.70 | — | — | |
| SCHEMBL10906622 | 0.67 | GAA (0.36) | ALDH1A1GAATSHRKMT2AL3MBTL1 | |
| SCHEMBL4272718 | 0.65 | ALDH1A1 (0.56) | ALDH1A1GAATSHRLMNAKMT2A | |
| SCHEMBL10905758 | 0.63 | ALDH1A1 (0.39) | ALDH1A1LMNAKMT2AL3MBTL1HPGD | |
| SCHEMBL6517665 | 0.63 | CYP1A2 (0.53) | ALDH1A1GAATSHRLMNAKMT2A | |
| SCHEMBL10907585 | 0.62 | CASP1 (0.45) | ALDH1A1GAATSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |