Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907628 | 0.99 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10CYP19A1 | |
| SCHEMBL10416239 | 0.72 | SLC6A3 (0.40) | KDM4EALDH1A1HPGDHSD17B10CYP19A1 | |
| SCHEMBL10786756 | 0.71 | CYP19A1 (0.34) | KDM4EALDH1A1HPGDHSD17B10CYP19A1 | |
| SCHEMBL10843729 | 0.71 | PPOX (0.42) | — | |
| SCHEMBL10546043 | 0.70 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL10598977 | 0.69 | GRM7 (0.33) | — | |
| SCHEMBL10596296 | 0.67 | SLC6A3 (0.42) | KDM4EALDH1A1HPGDHSD17B10SLC6A3 | |
| SCHEMBL9765187 | 0.66 | SLC6A3 (0.41) | ALDH1A1SLC6A3LMNA | |
| SCHEMBL10786741 | 0.66 | PPOX (0.38) | — | |
| SCHEMBL10416238 | 0.66 | SLC6A3 (0.40) | ALDH1A1HPGDSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4595409-A | Substituted phenyl-4,5,6,7-tetrahydro-2H-isoindole-1,3-diones, and their production and use | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1986-06-17 | — | — | US | claimed |
| EP-0142648-A1 | 2-Substituted phenyl-4,5,6,7-tetrahydro-2h-isoindole-1,3 diones, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-05-29 | — | — | EP | claimed |