SCHEMBL10907461

SCHEMBL10907461

CCC(Oc1ccccc1)C(C)(Cl)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
TSHR P16473 2/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
MAPT P10636 1/20 0.38
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PPARA Q07869 3/20 0.37
PPARG P37231 2/20 0.37
NPSR1 Q6W5P4 2/20 0.36
HPGD P15428 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5822901 0.78 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AMTNR1AMTNR1B
SCHEMBL12868248 0.77 ATM (0.37) ALDH1A1MTNR1AMTNR1BTSHRMAPT
SCHEMBL11474769 0.76 CYP2C19 (0.42) ALDH1A1MTNR1AMTNR1BTSHRMAPT
SCHEMBL10940204 0.76 PPARG (0.39) ALDH1A1MTNR1AMTNR1BTSHRMAPT
SCHEMBL13990822 0.74 LTA4H (0.38) ALDH1A1MTNR1AMTNR1BLMNA
SCHEMBL29444639 0.73 PPARA (0.50) MEN1KMT2ATSHRMAPTPPARA
SCHEMBL2884339 0.73 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ATSHRL3MBTL1
SCHEMBL27594813 0.71 RIPK1 (0.43) ALDH1A1MEN1KMT2ACRHBPCRHR2
SCHEMBL10907459 0.71 MTNR1A (0.40) ALDH1A1MEN1KMT2AMTNR1AMTNR1B
SCHEMBL8132529 0.71 PPARA (0.40) ALDH1A1MEN1KMT2AMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4613330-A Delivery system for desired agents MICHELSON PAUL E 1986-09-23 US disclosed