Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 4/20 | 0.47 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CBX7 | O95931 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338942 | 0.93 | HPSE (0.52) | HPSETIMP3MEN1KMT2AUSP2 | |
| SCHEMBL10907541 | 0.87 | HPSE (0.46) | HPSETIMP3MEN1KMT2AUSP2 | |
| SCHEMBL10907894 | 0.86 | ENPP2 (0.45) | HPSETIMP3MEN1KMT2AUSP2 | |
| SCHEMBL11428137 | 0.85 | CASP6 (0.47) | HPSETIMP3MEN1KMT2AUSP2 | |
| SCHEMBL10907776 | 0.85 | TIMP3 (0.50) | TIMP3MEN1KMT2APRMT1TNNI3 | |
| SCHEMBL10909166 | 0.83 | ENPP2 (0.43) | HPSETIMP3MEN1KMT2AUSP2 | |
| SCHEMBL10909132 | 0.83 | ENPP2 (0.50) | HPSETIMP3MEN1KMT2AUSP2 | |
| SCHEMBL10905493 | 0.83 | NT5E (0.59) | HPSETIMP3MEN1KMT2AUSP2 | |
| SCHEMBL10909738 | 0.83 | MEN1 (0.47) | HPSETIMP3MEN1KMT2AUSP2 | |
| SCHEMBL11427748 | 0.83 | CASP6 (0.47) | HPSETIMP3MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |