Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 3/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | FGF1 | P05230 | 1/20 | 0.42 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CD40 | P25942 | 1/20 | 0.40 |
| ▸ | CD40LG | P29965 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351829 | 0.93 | TIMP3 (0.58) | TIMP3CASP6CTDSP1ENPP2APEX1 | |
| SCHEMBL10907420 | 0.92 | CASP6 (0.52) | TIMP3CASP6CTDSP1ENPP2APEX1 | |
| SCHEMBL10908035 | 0.87 | RECQL (0.53) | TIMP3ENPP2APEX1ING2PRMT1 | |
| SCHEMBL11424939 | 0.86 | CASP6 (0.57) | TIMP3CASP6CTDSP1ENPP2APEX1 | |
| SCHEMBL10908640 | 0.85 | L3MBTL1 (0.44) | TIMP3APEX1PRMT1MEN1KMT2A | |
| SCHEMBL11352189 | 0.84 | TIMP3 (0.57) | TIMP3CASP6CTDSP1ENPP2APEX1 | |
| SCHEMBL10908164 | 0.84 | TIMP3 (0.51) | TIMP3CASP6CTDSP1APEX1F11 | |
| SCHEMBL11431164 | 0.83 | MAPT (0.56) | CASP6MEN1KMT2ACD40CD40LG | |
| SCHEMBL10905317 | 0.83 | TIMP3 (0.50) | TIMP3CASP6CTDSP1APEX1F11 | |
| SCHEMBL10909110 | 0.83 | CTDSP1 (0.50) | TIMP3CASP6CTDSP1ENPP2APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |