Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 3/20 | 0.43 |
| ▸ | CD40LG | P29965 | 3/20 | 0.43 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | FGF1 | P05230 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341156 | 0.93 | TIMP3 (0.48) | CD40CD40LGTIMP3NAMPTCA1 | |
| SCHEMBL10907792 | 0.89 | KMT2A (0.47) | TIMP3TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL11433615 | 0.88 | CASP6 (0.51) | CD40CD40LGCA1CA2CTDSP1 | |
| SCHEMBL10907955 | 0.86 | CD40 (0.44) | CD40CD40LGTIMP3NAMPTCA1 | |
| SCHEMBL10907712 | 0.86 | MPL (0.46) | CD40CD40LGTIMP3CA1CA2 | |
| SCHEMBL11439393 | 0.83 | CD40 (0.57) | CD40CD40LGCA1CA2CTDSP1 | |
| SCHEMBL10908078 | 0.83 | HPSE (0.44) | CD40CD40LGTIMP3NAMPTKMT2A | |
| SCHEMBL10909164 | 0.83 | CD40 (0.47) | CD40CD40LGTIMP3NAMPTCA1 | |
| SCHEMBL10907905 | 0.82 | MPL (0.48) | CD40CD40LGTIMP3CA1CA2 | |
| SCHEMBL11337777 | 0.82 | TIMP3 (0.54) | TIMP3CA1CA2TNNI3TNNT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |