Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6291911 | 0.80 | SIGMAR1 (0.46) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9834050 | 0.80 | PDGFRB (0.58) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL121810 | 0.79 | MEN1 (0.54) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11697405 | 0.78 | ALDH1A1 (0.56) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL126110 | 0.78 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL14078326 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3894477 | 0.77 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16398166 | 0.77 | RAB9A (0.52) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16397904 | 0.77 | NPC1 (0.49) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL7641250 | 0.77 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599357-A | 1-mercaptoalkanoylindoline-2-carboxylic acids | CIBA-GEIGY CORPORATION (US) | 1986-07-08 | — | — | US | disclosed |