Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRYZ | Q08257 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909426 | 0.84 | CRYZ (0.45) | CRYZNPSR1NPC1RAB9AKDM4E | |
| SCHEMBL10906319 | 0.80 | CRYZ (0.42) | CRYZHPGDNPSR1NPC1RAB9A | |
| SCHEMBL10909609 | 0.76 | CRYZ (0.40) | CRYZNPSR1KDM4EALOX15MAPK1 | |
| SCHEMBL10908639 | 0.75 | CRYZ (0.42) | CRYZNPSR1KDM4EALOX15MAPK1 | |
| SCHEMBL10909288 | 0.75 | ADRA2A (0.42) | CRYZNPSR1KDM4EALOX15MAPK1 | |
| SCHEMBL10909406 | 0.74 | NPSR1 (0.44) | CRYZNPSR1KDM4EALOX15MAPK1 | |
| SCHEMBL10908627 | 0.70 | CRYZ (0.40) | CRYZNPSR1MAPTKDM4EALOX15 | |
| SCHEMBL10908632 | 0.69 | CRYZ (0.40) | CRYZNPSR1KDM4EALOX15MAPK1 | |
| SCHEMBL6693720 | 0.68 | CRYZ (0.71) | CRYZNPSR1KDM4EALOX15MAPK1 | |
| SCHEMBL10908405 | 0.66 | CRYZ (0.46) | CRYZNPSR1KDM4EALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618692-A | ANTITUMOR AGENTS | ASTA-WERKE AKTIENGESELLSCHAFT (DE) | 1986-10-21 | — | — | US | disclosed |