Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CRYZ | Q08257 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 11/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909609 | 0.85 | CRYZ (0.40) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| SCHEMBL10908639 | 0.84 | CRYZ (0.42) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| SCHEMBL10909406 | 0.81 | NPSR1 (0.44) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| SCHEMBL10908627 | 0.76 | CRYZ (0.40) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| SCHEMBL10908573 | 0.75 | CRYZ (0.43) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| 4-Hydroxycyclophosphamide SCHEMBL17737224 | 0.74 | NPSR1 (0.54) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| Lomustine SCHEMBL168490 | 0.73 | ADRA2A (0.64) | ADRA2APDE4AADRA1ANPSR1KDM4E | |
| SCHEMBL17899474 | 0.68 | NPSR1 (0.57) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| Perfosfamide SCHEMBL1650261 | 0.67 | NPSR1 (0.49) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| Perfosfamide SCHEMBL4652 | 0.67 | NPSR1 (0.49) | NPSR1KDM4EALOX15MAPK1CRYZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618692-A | ANTITUMOR AGENTS | ASTA-WERKE AKTIENGESELLSCHAFT (DE) | 1986-10-21 | — | — | US | disclosed |