Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CRYZ | Q08257 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908627 | 0.82 | CRYZ (0.40) | NPSR1CRYZKDM4EALOX15MAPK1 | |
| SCHEMBL10909609 | 0.82 | CRYZ (0.40) | NPSR1CRYZKDM4EALOX15MAPK1 | |
| SCHEMBL10908639 | 0.81 | CRYZ (0.42) | NPSR1CRYZKDM4EALOX15MAPK1 | |
| SCHEMBL10909288 | 0.81 | ADRA2A (0.42) | NPSR1CRYZKDM4EALOX15MAPK1 | |
| 4-Hydroxycyclophosphamide SCHEMBL406857 | 0.77 | NPSR1 (0.54) | NPSR1CRYZKDM4EALOX15MAPK1 | |
| 4-Hydroxycyclophosphamide SCHEMBL17737224 | 0.77 | NPSR1 (0.54) | NPSR1CRYZKDM4EALOX15MAPK1 | |
| SCHEMBL10906319 | 0.76 | CRYZ (0.42) | NPSR1CRYZKDM4EALOX15MAPK1 | |
| SCHEMBL10909426 | 0.76 | CRYZ (0.45) | NPSR1CRYZKDM4EALOX15MAPK1 | |
| SCHEMBL10908573 | 0.74 | CRYZ (0.43) | NPSR1CRYZKDM4EALOX15MAPK1 | |
| SCHEMBL17635575 | 0.73 | NPSR1 (0.50) | NPSR1CRYZKDM4EALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618692-A | ANTITUMOR AGENTS | ASTA-WERKE AKTIENGESELLSCHAFT (DE) | 1986-10-21 | — | — | US | disclosed |