Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 8/20 | 0.57 |
| ▸ | CTSK | P43235 | 8/20 | 0.57 |
| ▸ | REN | P00797 | 5/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | CASP4 | P49662 | 1/20 | 0.49 |
| ▸ | CASP5 | P51878 | 1/20 | 0.49 |
| ▸ | CASP9 | P55211 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.49 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.49 |
| ▸ | NMBR | P28336 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907849 | 0.90 | CTSB (0.62) | CTSBCTSKRENCASP1CASP3 | |
| SCHEMBL10907853 | 0.88 | CTSB (0.54) | CTSBCTSKRENCASP3CASP7 | |
| SCHEMBL10909457 | 0.83 | REN (0.54) | CTSBCTSKRENCASP1 | |
| SCHEMBL10909792 | 0.83 | CTSB (0.55) | CTSBCTSKRENCASP3CASP7 | |
| SCHEMBL10908290 | 0.83 | CTSK (0.52) | CTSBCTSKREN | |
| SCHEMBL10908060 | 0.81 | CTSK (0.51) | CTSBCTSKRENCASP1CASP3 | |
| SCHEMBL10909548 | 0.81 | CTSB (0.53) | CTSBCTSKREN | |
| SCHEMBL10909559 | 0.81 | CTSK (0.51) | CTSBCTSKRENCASP1CASP3 | |
| SCHEMBL10907982 | 0.81 | CASP3 (0.51) | CTSBCTSKRENCASP3CASP7 | |
| SCHEMBL10557805 | 0.80 | MAPT (0.57) | CTSBCTSKCASP1CASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |